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We Give Aminoglycoside Antibiotics at the End of Hemodialysis
Author(s) -
Eyler Rachel
Publication year - 2016
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/sdi.12489
Subject(s) - medicine , aminoglycoside , dosing , intensive care medicine , dialysis , antibiotics , hemodialysis , pharmacology , microbiology and biotechnology , biology
Abstract We often administer dialyzable medications after dialysis to ensure that adequate concentrations are maintained in the body until the next session. In the case of aminoglycosides, we may have the opportunity to dose more aggressively predialysis, and then use the clearance of the drug by dialysis to limit toxicities. Predialysis aminoglycoside dosing is intriguing, although studies evaluating the safety and efficacy of this approach are necessary before it can be used routinely.