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C‐reactive Protein: Repeated Measurements will Improve Dialysis Patient Care
Author(s) -
Cobo Gabriela,
Qureshi Abdul Rashid,
Lindholm Bengt,
Stenvinkel Peter
Publication year - 2015
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/sdi.12440
Subject(s) - medicine , inflammation , dialysis , intensive care medicine , c reactive protein , kidney disease , biomarker , disease , systemic inflammation , clinical practice , physical therapy , biochemistry , chemistry
Systemic inflammation is a common feature in the uremic phenotype and associates with poor outcomes. The awareness regarding the importance of inflammation assessment in chronic kidney disease ( CKD ) patients has risen in recent years, and despite the development of novel biomarkers, C‐reactive protein ( CRP ) is still the most measured inflammatory parameter. Notwithstanding, the possible weak points of CRP determination, this biomarker has demonstrated being useful both for guidance in clinical practice and for risk estimation. In addition, regular determination of CRP among dialysis patients has been associated with better outcomes in different dialysis facilities. Because persistent inflammation may be a silent reflection of various pathophysiologic alterations in CKD , it is crucial that inflammatory markers are regularly monitored and therapeutic attempts be made to target this inflammation.