Premium
From Basic Biology to Randomized Clinical Trial: The B eta R adiation for A rterio V enous Graft O utflow Stenosis (BRAVO II)
Author(s) -
RoyChaudhury Prabir,
Arnold Perry,
Seigel Jeff,
Misra Sanjay
Publication year - 2012
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/sdi.12000
Subject(s) - medicine , randomized controlled trial , context (archaeology) , stenosis , radiation therapy , angioplasty , external beam radiation , surgery , radiology , paleontology , biology
The BRAVO‐II study was a randomized controlled study of endovascular radiation therapy as compared to sham radiation therapy, following angioplasty of a thrombosed PRFE graft. The results did not show a benefit of endovascular radiation therapy, albeit in the context of an early termination of the study at less than 50% enrollment due to business reasons. Emphasis is laid on the fact that there may still be a role for radiation therapy in specific clinical settings associated with dialysis vascular access dysfunction.