Premium
Medication‐related fibrovascular hyperplasia lesion in tongue: Case report
Author(s) -
Ballardin Bárbara Soldatelli,
Mobile Rafael Zancan,
TorresPereira Cassius Carvalho,
Schussel Juliana Lucena
Publication year - 2020
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/scd.12497
Subject(s) - medicine , immunosuppression , tongue , nodule (geology) , hyperplasia , biopsy , lymphoma , lesion , granulation tissue , oral mucosa , medical history , dermatology , pathology , surgery , paleontology , wound healing , biology
Objective The objective of this study is to report the case of a patient who underwent hematopoietic stem cell transplantation for Hodgkin's lymphoma treatment and developed multiple tongue lesions during recovery. Methods and results This is the case report of a patient who developed ulcerated lesions with areas of depapillation on the border and dorsum of the tongue. The ulcer evolved to a reddish fibrous hyperplastic nodule, similar to adjacent mucosa. The patient was using a series of medications, such as antifungals, antibiotics, antivirals, corticosteroids, and analgesics in addition to immunosuppression with cyclosporine. Considering the medical history of the patient, a biopsy was performed. Histopathological analyses describe hyperplasia, granulation tissue, vascular proliferation, and intense inflammatory infiltrate, and the diagnosis was of medication‐related fibrovascular hyperplasia (MRFH). Conclusion Patients in use of cyclosporine are at risk to develop oral lesions, such as MRFH. The correct diagnosis is important, so the adequate treatment and follow‐up are instituted even considering the immunosuppression protocol.