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Dental management of a child with Wiskott Aldrich syndrome prior to bone marrow transplant: A case report
Author(s) -
Santosh Anitha,
Banthiya Karun,
Deshmukh C.T.,
Bhange Prasad,
Shah Shagun,
Kakade Adesh
Publication year - 2020
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/scd.12452
Subject(s) - medicine , hematologist , immunosuppression , intensive care medicine , bone marrow failure , bone marrow transplant , hematopoietic stem cell transplantation , bone marrow transplantation , transplantation , pediatrics , surgery , dentistry , stem cell , haematopoiesis , disease , biology , genetics
Aim Orodental manifestations are commonly presented in Wiskott Aldrich Syndrome (WAS). The purpose of this paper is to report a case of dental management of a 5‐year‐old male child with WAS before Hematopoietic Stem Cell Transplantation (HSCT). Such patients are more prone to infection due to pretransplantation chemotherapy and posttransplantation immunosuppression; thus, it becomes imperative to eliminate all potential sources of infection before transplantation. Materials and Methods Fluctuating blood parameters before the dental procedure was an important challenge in rendering dental treatment. Dental procedures were carried out under general anesthesia by maintaining the hematological parameters with blood and platelet transfusion. The conventional dental treatment may not be applicable in such patients as failure of dental treatment can cause the failure of HSCT, and it has to be modified based on the clinical acumen and recommendations. Conclusions This case report focuses on the measures to be taken before, during, and after the dental procedure to ensure the success of the dental therapy and prevent failure of HSCT due to residual dental foci of infection. A multidisciplinary approach involving a pedodontist, a pediatrician, and a hematologist can improve the quality of life of such patients.