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Peripheral T‐cell non‐Hodgkin lymphoma manifesting as a primary lesion on the lip: A rare case report
Author(s) -
dos Santos Heloísa Laís Rosário,
Alves Carolina Guimarães Bonfim,
Almendra Mattos Rafaela Maia,
Curi Davi Silva Carvalho,
Leite Ribeiro Patricia,
Sarmento Viviane Almeida
Publication year - 2018
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/scd.12333
Subject(s) - medicine , lesion , lymphoma , chemotherapy , disease , non hodgkin's lymphoma , hard palate , pathology , oral cavity , rare disease , immunohistochemistry , surgery , dentistry
Primary manifestations of extraganglion non‐Hodgkin lymphoma (NHL) from T‐cells in the oral cavity are rare and often difficult to diagnose. Herein, we describe a case of T‐cell NHL with a primary lesion on the lip diagnosed with a 25‐year‐old woman. The patient reported the appearance of the initial lesion on the upper lip, which advanced to the hard palate and oral mucosa. Histological examination and immunohistochemistry were compatible with peripheral T‐cell NHL without further specifications. The proposed treatment consisted of six cycles of multiagent chemotherapy. The patient died from complications of the disease before the third cycle of chemotherapy. Understanding the clinical signs of lymphoma is important for the early diagnosis of this disease to avoid aggressive and potentially fatal behavior.