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Intraoral granulocytic sarcoma as a manifestation of myelofibrosis: A case report and review of the literature
Author(s) -
Nunes Laiz Fernandes Mendes,
Rocha Amanda Leal,
Magalhães, Gustavo Henrique Romani,
de Melo, Frederico Henrique Corrêa,
Travassos Denise Vieira,
Mesquita Ricardo Alves,
Silva Tarcília Aparecida
Publication year - 2018
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/scd.12325
Subject(s) - myelofibrosis , medicine , myeloproliferative disorders , sarcoma , dermatology , lesion , pathology , leukemia , bone marrow
Granulocytic sarcoma (GS) is an extramedullary tumor associated with myelodysplastic syndromes or myeloproliferative diseases. Intraoral manifestations are considered uncommon, with a reasonable number of cases, and are mostly related to leukemia. The association of oral GS and myelofibrosis is very rare and only three cases have been published. In this paper, we report the fourth case of oral lesion in a patient with a diagnosis of myelofibrosis. The aim of this study was to present a review of the literature, discussing the current and previous cases of oral GS associated with myelofibrosis or other hematological disorders and the importance of accurate diagnosis through clinical, microscopic, and immunohistochemical features.