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Cowden syndrome—a case report emphasizing the role of the dental surgeon in diagnosis
Author(s) -
Webber Liana Preto,
Martins Manoela Domingues,
Carrard Vinícius Coelho,
Trevizani Martins Marco Antônio,
Munerato Maria Cristina
Publication year - 2014
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/scd.12081
Subject(s) - medicine , cowden syndrome , macrocephaly , dermatology , hamartoma , nodule (geology) , family history , thyroid , medical history , dental surgeon , pathology , radiology , dentistry , pten , apoptosis , paleontology , biochemistry , chemistry , pi3k/akt/mtor pathway , biology
Cowden syndrome or multiple hamartoma syndrome, is a rare genetic condition inherited in an autosomal dominant pattern characterized by cutaneous manifestations, polyps, thyroid gland neoplasias, and macrocephaly. This report presents the case of a 36‐year‐old patient who looked for dental treatment for a gingival nodule. Current and past medical history and oral and facial manifestations led to the diagnosis of Cowden syndrome. This case report emphasizes the role of the dental surgeon in the diagnosis of this systemic disease, based on the analysis of medical history and manifestations in the oral cavity.