Open AccessSleep reduction: A link to other neurobiological diseases
Author(s) -
Kumar Anil,
Chanana Priyanka
Publication year - 2014
Publication title -
sleep and biological rhythms
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.371
H-Index - 30
eISSN - 1479-8425
pISSN - 1446-9235
DOI - 10.1111/sbr.12066
Subject(s) - sleep (system call) , disease , sleep deprivation , anxiety , medicine , neurology , depression (economics) , sleep disorder , cognition , psychology , neuroscience , psychiatry , computer science , economics , macroeconomics , operating system
Sleep is a restorative mechanism of the body to maintain optimal health. Its physiological role in relaxation, repair and maintenance of psychological balance is well known. Alternatively, sleep deprivation ( SD ) or sleep loss is kind of stress that is associated with a number of neurobehavioral, metabolic, hormonal, neuroendocrine and immune disorders of the body. SD or fragmentation is also involved in several neurological diseases such as anxiety, depression and cognitive impairments. In the present article, the authors highlight neurological problems associated with SD such as A lzheimer's disease, P arkinson's disease, epilepsy, pain, and H untington's disease. They focus on various neurological disorders either induced or worsened by SD and sleep loss along with the proposed mechanisms involved. As one of the greatest present challenges for clinicians is the inadequate drug therapy for sleep disorders, it has become essential to identify individuals at risk because recognition and adequate treatment of their sleep problems may reduce the risk of certain neurological disorders.