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Adaptive design in surveys and clinical trials: similarities, differences and opportunities for cross‐fertilization
Author(s) -
Rosenblum Michael,
Miller Peter,
Reist Benjamin,
Stuart Elizabeth A.,
Thieme Michael,
Louis Thomas A.
Publication year - 2019
Publication title -
journal of the royal statistical society: series a (statistics in society)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.103
H-Index - 84
eISSN - 1467-985X
pISSN - 0964-1998
DOI - 10.1111/rssa.12438
Subject(s) - protocol (science) , computer science , adaptation (eye) , data collection , identification (biology) , population , clinical trial , research design , early stopping , computerized adaptive testing , data mining , risk analysis (engineering) , psychology , machine learning , statistics , medicine , mathematics , clinical psychology , alternative medicine , psychometrics , neuroscience , biology , artificial neural network , botany , environmental health , pathology
Summary Adaptive designs involve preplanned rules for modifying an on‐going study based on accruing data. We compare the goals and methods of adaptation for trials and surveys, identify similarities and differences, and make recommendations for what types of adaptive approaches from one domain have high potential to be useful in the other. For example, clinical trials could benefit from recently developed survey methods for monitoring which groups have low response rates and intervening to fix this. Clinical trials may also benefit from more formal identification of the target population, and from using paradata (contextual information collected before or during the collection of actual outcomes) to predict participant compliance and retention and then to intervene to improve these. Surveys could benefit from stopping rules based on information monitoring, applying techniques from sequential multiple‐assignment randomized trial designs to improve response rates, prespecifying a formal adaptation protocol and including a data monitoring committee. We conclude with a discussion of the additional information, infrastructure and statistical analysis methods that are needed when conducting adaptive designs, as well as benefits and risks of adaptation.