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Handheld flow meter improves COPD detectability regardless of using a conventional questionnaire: A split‐sample validation study
Author(s) -
Fujita Misuzu,
Nagashima Kengo,
Takahashi Sho,
Suzuki Kiminori,
Fujisawa Takehiko,
Hata Akira
Publication year - 2020
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/resp.13602
Subject(s) - medicine , copd , peak flow meter , physical therapy , sample (material) , sample size determination , statistics , asthma , mathematics , chemistry , chromatography
Background and objective Improved detectability of chronic obstructive pulmonary disease (COPD) using a handheld flow meter (HFM) with symptom‐based questionnaires has not been sufficiently evaluated. This study aimed to identify the benefit of using an HFM in COPD screening. Methods A total of 2008 participants, who were ≥ 40 years of age, from Isumi City, Japan, were recruited. We developed two novel point systems for detecting COPD, one incorporated score of HFM alone (sHFM) and the other incorporated the score of International Primary Care Airway Group questionnaire (IPAG) and HFM (sIPAG + HFM). Validation using random sample allocation (split‐sample validation) was carried out to assess the predictive performance of these models. Results Participants were assigned to a data set for model creation ( n = 1007) or a data set for model assessment ( n = 1001) to perform split‐sample validation. Decision curve analysis showed that the net benefits of sHFM and sIPAG + HFM were higher than that of the IPAG score (sIPAG) and specificity of the former two were also significantly higher than that of sIPAG. However, the curves of sHFM and sIPAG + HFM were crossing and practically the same with no significant difference in sensitivity and specificity. Conclusion This study confirms that HFM is significantly advantageous in detecting COPD despite the use of a conventional questionnaire.