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POLY‐UNSATURATED FATTY ACIDS METABOLOMICS STUDY REVEALS CHILDHOOD SERUM HETES LEVELS CLOSELY RELATED TO GLUTATHIONE PEROXIDASES IN ALLERGIC ASTHMA
Author(s) -
KUANG-YU CHEN
Publication year - 2018
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/resp.13420_351
Subject(s) - medicine , asthma , metabolomics , peroxidase , glutathione , glutathione peroxidase , biochemistry , immunology , endocrinology , enzyme , oxidative stress , bioinformatics , biology , catalase
medical record in one community hospital during October 2014 to September 2015. Situation of asthma exacerbation was survey from patients with recurrent asthma exacerbation at least 2 times per year and in-depth interview healthcare providers, patient and caregivers. Results: 346 patients have recurrent emergency room visited at least 2 times /year. 80.35 % with average age 2.7 .43 years old. The rate of recurrent asthma exacerbation 2.8 .06 times per patient. The average length time to recurrent asthma exacerbation was 51.0 9.39 days. 283 patients (81.79%) were not prescribed inhale corticosteroid; in this group 108 patients (38.2%) had more than 3 times of asthma exacerbation and should be considered to start inhale corticosteroid. Content analyses from healthcare provider’s perspectives about problems of asthma exacerbation were under diagnosis or delay diagnosis leading to delay treatment with inhale corticosteroid, non-adherence of medication and trigger. From patients or caregivers ‘perspective about problems of asthma exacerbation were weather change, no emergency bronchodilator supplies, loss follow up, incorrect technique of inhalation. Conclusion: The situation of asthma exacerbation so healthcare provider should be concern for asthma exacerbation management effectively.