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Type 2 diabetes is associated with a higher incidence of hospitalization for pulmonary embolism in Spain: Analysis of hospital discharge data during 2004–2013
Author(s) -
MiguelDíez Javier,
MuñozRivas Nuria,
JiménezGarcía Rodrigo,
HernándezBarrera Valentín,
CarrascoGarrido Pilar,
Monreal Manuel,
Jiménez David,
Guijarro Ricardo,
López de Andrés Ana
Publication year - 2016
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/resp.12847
Subject(s) - medicine , incidence (geometry) , pulmonary embolism , diabetes mellitus , atrial fibrillation , type 2 diabetes mellitus , charlson comorbidity index , hospital discharge , comorbidity , endocrinology , physics , optics
ABSTRACT Background and objective We compared the incidence and outcome of pulmonary embolism ( PE ) in individuals with and without type 2 diabetes mellitus ( T2DM ) in Spain during 2004–2013. Methods The study was based on National Hospital Discharge Data, and the study population comprised patients hospitalized for PE . Annual incidence rates were classified according to T2DM status. In‐hospital mortality ( IHM ), length of hospital stay ( LOHS ), comorbidities and use of diagnosis and therapeutic procedures were analysed. Results We identified 123 872 discharges of patients (56 361 men and 67 511 women) with PE as their primary diagnosis (15.3% with T2DM ). Incidence of discharge diagnoses of PE increased significantly in all groups. Crude rates were higher in diabetic patients. A positive association was identified between T2DM and PE : adjusted IRR was 2.00 (95% CI : 1.95–2.05) for men and 2.50 (95% CI : 2.45–2.57) for women. LOHS , readmissions and IHM decreased significantly for both groups. An association between IHM and risk factors (older age, Charlson comorbidity index >3, atrial fibrillation and cancer) was observed. T2DM was associated with higher IHM in men ( OR : 1.22, 95% CI : 1.12–1.32) and women ( OR : 1.24, 95% CI : 1.15–1.33). The use of computed tomography pulmonary angiography increased significantly overtime. Conclusion We confirmed that in both men and women, diabetes was an independent risk factor for IHM . The incidence of discharge of patients with PE increased significantly during the study period. Diabetic men and women had a higher risk of hospitalization for PE than non‐diabetic men and women. Diabetic women had higher IHM than diabetic men.