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Correlation between heart rate variability indexes and aerobic physiological variables in patients with COPD
Author(s) -
Leite Marceli R.,
Ramos Ercy Mara C.,
KalvaFilho Carlos A.,
Rodrigues Fernanda Maria M.,
Freire Ana Paula C.F.,
Tacao Guilherme Y.,
Toledo Alessandra C.,
Cecílio Michel J.,
Vanderlei Luiz Carlos M.,
Ramos Dionei
Publication year - 2015
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/resp.12424
Subject(s) - medicine , copd , heart rate variability , cardiology , anaerobic exercise , pulmonary disease , aerobic exercise , heart rate , vo2 max , correlation , physical therapy , blood pressure , mathematics , geometry
Abstract Background and objective Previous studies have shown a relationship between the level of physical fitness and autonomic variables. However, these relationships have not been investigated in patients with chronic obstructive pulmonary disease ( COPD ). The objective of this study was to correlate the resting heart rate variability ( HRV ) indexes with aerobic physiological variables obtained at a maximal exercise test in patients with COPD . Methods Thirty‐seven patients with COPD (63 (59–70) years; 46 (35.4–63.7) forced expiratory volume in 1 s ( FEV 1 )%) underwent assessment of autonomic modulation at rest for 20 min to determine the HRV indexes in time and frequency domains. Soon after that, the patients performed an incremental exercise test to determine the anaerobic threshold (GET), the peak oxygen uptake ( VO 2PEAK ) and the velocity corresponding to VO 2PEAK ( vVO 2PEAK ). Results The indexes that express parasympathetic component as RMSSD (11.4 [7.5–23.8], HF (ms 2 ) (35 [17–195] and SD 1 (8.1 [5.3–16.8]), correlated with GET ( r = 0.39; r = 0.43; r = 0.39 respectively). The indexes that represent the overall variability, SDNN (19.5 [13.9–28.8]), LF (ms 2 ) (111 [38–229]), and SD2 (26.8 [18.6–35.4]) correlated with vVO 2PEAK ( r = 0.37; r = 0.38; r = 0.37; r = 0.44; r = 0.43; r = 0.46 respectively). Likewise, the indexes LF (ms 2 ), LF (nu) (63.2 [46–77,9]), HF (nu) (36.8 [22.1–54]), and LF/HF (1.7 [0.9–3.5]) correlated with VO 2PEAK ( r = 0.35; r = 0.35; r = −0.35; r = 0.40 respectively). Conclusions This study demonstrated that HRV indexes at rest may become a predictive tool for aerobic capacity in COPD patients after the development of more consistent methods.