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Comparison of the modified shuttle walk test and cardiopulmonary exercise test in sarcoidosis
Author(s) -
Boer Sally,
Kolbe John,
Wilsher Margaret L.
Publication year - 2014
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/resp.12276
Subject(s) - medicine , dlco , vital capacity , vo2 max , diffusing capacity , cardiology , pulmonary function testing , sarcoidosis , pulmonary diffusing capacity , lung volumes , physical therapy , cycle ergometer , heart rate , lung function , lung , blood pressure
Background and objective Dyspnoea and exercise intolerance are common in sarcoidosis and are often poorly correlated with resting lung function. Measurement of peak exercise capacity is likely to be helpful in assessing and monitoring disease. The aim of this study was to compare the modified shuttle walk test ( MSWT ) to cardiopulmonary exercise test ( CPET ) as a measure of peak exercise capacity in sarcoidosis. Methods Thirty‐three (17 male, mean age 48 years) patients with sarcoidosis completed a standardized exponential exercise protocol cycle ergometer CPET and a single corridor MSWT in random order. Results Subjects has a mean forced expiratory volume in 1 s ( FEV 1 ) 2.4 L (75.7%predicted), forced vital capacity ( FVC ) 3.43 L (88.7%predicted) and diffusing capacity for carbon monoxide (DLCO) 20.3 mL/min/mm Hg (71.4%predicted). There was a strong correlation between MSWT distance and peak oxygen uptake ( VO 2 ) during CPET (r = 0.87; P < 0.0001), and between maximum heart rate during MSWT and CPET (r = 0.82; P < 0.0001). There was a moderate correlation between FEV 1 , FVC and DLCO with MSWT distance (r = 0.55, r = 0.61, r = 0.61, respectively; all P < 0.001) and with peak VO 2 (r = 0.62, r = 0.63, r = 0.62, respectively; all P < 0.0001). Conclusions Peak VO 2 achieved during CPET strongly correlated with MSWT distance. MSWT is a measure of peak exercise capacity in sarcoidosis that does not require equipment and can be readily available in the clinic.