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Role of extracellular vesicles in intercellular communication during reproduction
Author(s) -
Godakumara Kasun,
Dissanayake Keerthie,
Hasan Mohammad Mehedi,
Kodithuwakku Suranga. P.,
Fazeli Alireza
Publication year - 2022
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/rda.14205
Subject(s) - gamete , reproduction , embryo , microbiology and biotechnology , biology , human fertilization , extracellular , intracellular , embryogenesis , extracellular vesicles , genetics
The mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent embryo and the maternal system. Extracellular vesicles (EVs) are involved in these communications to a significant degree from the gamete production and maturation to fertilization, embryo development and implantation. They regulate the cellular physiology and the immune reaction to bring about a favourable environment for a successful pregnancy. Deciphering the mechanisms employed in EV‐mediated embryo maternal communication could improve our knowledge in mammalian reproduction and increase the efficiency of animal breeding.