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Antioxidant response element activator, BTZO‐1, improves the developmental competence of bovine oocytes
Author(s) -
Aboelenain Mansour,
El_domany Wael B.,
Eldoumani Haitham,
Khalil Wael A.
Publication year - 2020
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/rda.13733
Subject(s) - blastocyst , oxidative stress , reactive oxygen species , antioxidant , activator (genetics) , andrology , apoptosis , embryo , competence (human resources) , microbiology and biotechnology , embryogenesis , biology , chemistry , biochemistry , medicine , gene , psychology , social psychology
Increased reactive oxygen species (ROS) generation may disrupt the oocytes function and their competence. In this study, we introduced BTZO‐1, a new supplement that can regulate the oxidative stress. Addition of BTZO‐1 during IVM of bovine oocytes improved their developmental competence in the term of improvement of blastocyst rates. In addition, the quality of the produced embryos was improved by decreasing the apoptosis level by showing a decreased number of TUNNEL positive cells.