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Identification of ectopic ovotestis in a dog with XX ovotesticular, SRY ‐negative, disorder of sexual development
Author(s) -
Diel de Amorim M,
Lerer A,
Durzi T,
Foster RA,
Gartley CJ
Publication year - 2018
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/rda.13174
Subject(s) - ovotestis , gonad , testis determining factor , biology , karyotype , disorders of sex development , pathology , endocrinology , medicine , andrology , anatomy , y chromosome , chromosome , genetics , gene
Contents A 1‐year‐old, previously spayed phenotypic female Poodle/Soft‐coated Wheaten Terrier (Whoodle) cross was presented for a suspected ovarian remnant. Serum luteinizing hormone ( LH ) concentration was below the detection limit (<1 ng/ml Witness ® LH ), and serum progesterone concentration was elevated in the chemiluminescence immunoassay ( CLIA ; 20 ng/ml), consistent with dioestrus and presence of ovarian tissue. Transabdominal ultrasound revealed a retroperitoneal soft tissue structure suspected to be a gonad. On exploratory laparotomy, a gonad was removed from the cranial retroperitoneum, cranial to the right kidney, after ligation of its primary blood supply. Histological examination proved the gonad to be an ovotestis. Subsequent cytogenetics revealed a 78 XX karyotype, thus confirming the diagnosis of ectopic ovotestis in a XX ovotesticular, SRY ‐negative, disorder of sexual development in a dog.