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Breed Variations in the Incidence of Pyometra and Mammary Tumours in Swedish Dogs
Author(s) -
Jitpean S,
Hagman R,
Ström Holst B,
Höglund OV,
Pettersson A,
Egenvall A
Publication year - 2012
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/rda.12103
Subject(s) - pyometra , breed , incidence (geometry) , medicine , veterinary medicine , prevalence , gynecology , epidemiology , biology , zoology , uterus , physics , optics
Contents Dogs enrolled in a Swedish insurance company (during 1995–2006) were studied for development of pyometra and mammary tumours ( MT s), with special attention to breed and age. There were over 260 000 female dogs with over 1 000 000 dog‐years at risk ( DYAR ) in the database, using data on bitches up to 10 years of age and 110 breeds with over 1000 DYAR . In total, 20 423 bitches were diagnosed with pyometra and 11 758 with MT s and 30 131 with either or both of the two diseases. The incidence rate ( IR ) for pyometra was 199 (95% CI 196–202), for MT s 112 (95% CI 110–114) and for either or both of the two diseases 297 (95% CI 294–301) dogs per 10 000 DYAR . The mean age of diagnosis pyometra was 7.0 years (SD ± 2.2), MT s 8.0 years (SD ± 1.6). In all breeds, the overall proportion of the bitches that developed disease by 10 years of age was for pyometra 19%, MT s 13%, and either or both of two diseases 30%. The top 10 breeds diagnosed with either or both of the two diseases were the Leonberger (73%), Irish Wolfhound (69%), Bernese Mountain Dog (69%), Great Dane (68%), Staffordshire Bull Terrier (66%), Rottweiler (65%), Bullterrier (62%), Doberman (62%), Bouvier des Flandres (60%), Airdaleterrier (60%). These data provide information of the combined disease incidence in a large number of different breeds. Breed variations in incidence rate suggests genetic components in disease development. Our study may be valuable in the search for genetic risk‐factors or protective factors.