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Control of AHPND by phages: a promising biotechnological approach
Author(s) -
Angulo Carlos,
LoeraMuro Abraham,
Trujillo Edgar,
LunaGonzález Antonio
Publication year - 2019
Publication title -
reviews in aquaculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.998
H-Index - 47
eISSN - 1753-5131
pISSN - 1753-5123
DOI - 10.1111/raq.12275
Subject(s) - vibrio harveyi , biology , vibrio parahaemolyticus , lytic cycle , vibrio , microbiology and biotechnology , shrimp , vibrio infections , bacterial disease , virology , bacteria , virus , fishery , genetics
Vibrio parahaemolyticus , V. campbellii , V. owensii and V. harveyi are causative agents of Acute Hepatopancreatic Necrosis Disease (AHPND) in shrimp. AHPND is recently one of the most important diseases worldwide because of the high mortality and huge economic losses in shrimp farms. Antibiotic resistance has caused concern into finding other options to fight against pathogenic bacterial diseases. Currently, the use of lytic phages has reemerged as a promising strategy to combat bacterial pathogens. Likewise, modern molecular tools have been applied to modify phages by genetic engineering to express specific antigens and antibodies. This study reviewed recent research reports in the development of phages to control Vibrio spp. infections in shrimp and discusses different specific strategies, placing them in perspective to combat AHPND.