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Cerebrovascular function response to prolonged sitting combined with a high‐glycemic index meal: A double‐blind, randomized cross‐over trial
Author(s) -
Burnet Kathryn,
Blackwell Jade,
Kelsch Elizabeth,
Hanson Erik D.,
Stone Keeron,
Fryer Simon,
Credeur Daniel,
Palta Priya,
Stoner Lee
Publication year - 2021
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/psyp.13830
Subject(s) - sitting , stroop effect , glycemic , psychology , cardiology , blood flow , medicine , meal , anesthesia , insulin , cognition , neuroscience , pathology
Acute prolonged sitting leads to cerebrovascular disruptions. However, it is unclear how prolonged sitting interacts with other common behaviors, including high‐ (HGI) and low‐glycemic index (LGI) meals. Using a double‐blind randomized cross‐over design, this study evaluated the effects of prolonged (3 hr) sitting, with a high‐ (HGI; GI: 100) or low‐glycemic index (LGI; GI: 19) meal on total brain blood flow (Q Brain ) and executive function. Eighteen young, healthy, active participants (22.6 [3.1] y, 33% F, 24.3 [3.7] kg/m 2 ) sat for 3 hr after consuming an HGI or LGI meal. Using Doppler ultrasound to measure internal carotid (ICA) and vertebral (VA) artery blood flow, Q Brain was calculated: (ICA blood flow + VA blood flow) × 2. Executive function was assessed using the Stroop Test and Trail Making Test—Part B. Brain fog was measured using a modified Borg Category Scale with Ratio properties (CR10). Following 3 hr of sitting, there was a significant decrease in Q Brain with time ( p = .001, ES = −0.26), though there were nonsignificant interaction ( p = .216) and condition effects ( p = .174). Brain fog increased ( p = .024, ES = 0.27) and Stroop reaction time worsened with time ( p = .001, ES: −0.40), though there were nonsignificant condition effects for brain fog ( p = .612) and the Stroop test ( p = .445). There was a nonsignificant condition effect ( p = .729) for the Trail Making Test—Part B, but completion time improved with time ( p = .001, ES = −0.40). In conclusion, 3 hr of prolonged sitting decreases Q Brain and executive function independent of glycemic index in young, healthy adults.