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Association between regional white and gray matter volume and ambiguity tolerance: Evidence from voxel‐based morphometry
Author(s) -
Tong Dandan,
Yang Wenjing,
Zhang Qinglin,
Li Wenfu,
Wei Dongtao,
Che Xianwei,
Zhang Meng,
Hitchman Glenn,
Qiu Jiang,
Liu Yijun,
Cao Guikang
Publication year - 2015
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/psyp.12433
Subject(s) - precuneus , psychology , white matter , voxel based morphometry , trait , gray (unit) , ambiguity , dorsolateral prefrontal cortex , voxel , cognitive psychology , prefrontal cortex , neuroscience , cognition , magnetic resonance imaging , medicine , linguistics , philosophy , computer science , radiology , programming language
The concept of tolerance of ambiguity (AT) is defined as the way in which an individual tends to perceive and deal with confusing, vague, and unclear situations. AT is generally considered as an important personality trait, but the neural mechanisms underlying individual differences in AT have never been investigated. Using voxel‐based morphometry and MSTAT‐II scale, we investigated the correlations between AT and regional white matter volume (rWMV) and regional gray matter volume (rGMV) in 351 young healthy subjects. We found AT to be positively correlated with rGMV in the dorsolateral prefrontal cortex (DLPFC), and negatively correlated with rGMV in the precuneus. These results indicate that increased rGMV in the left DLPFC may lead to characteristics of ambiguous stimuli consideration from multiple contexts and risk taking. Decreased rGMV in the left precuneus may be associated with a high tolerance for ambiguity, which attributes uncertainty to self‐related factors.