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Salivary 3‐methoxy‐4‐hydroxyphenylglycol increases after awakening in healthy young adults
Author(s) -
Sugaya Nagisa,
Izawa Shuhei,
Yamamoto Ryuichiro,
Ogawa Namiko,
Yajima Jumpei,
Okamura Hisayoshi,
Horiuchi Satoshi,
Tsuda Akira,
Nomura Shinobu
Publication year - 2015
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/psyp.12330
Subject(s) - heart rate , psychology , cortisol awakening response , medicine , ambulatory , saliva , heart rate variability , endocrinology , blood pressure , hydrocortisone
Levels of 3‐methoxy‐4‐hydroxyphenylglycol ( MHPG ) may reflect central noradrenergic activity. In this study, we investigated salivary MHPG changes after awakening, and explored their relationships with cortisol and peripheral autonomic activity. The participants were 25 college students. Saliva samples were collected on awakening and 30 min after awakening to determine MHPG and cortisol. Ambulatory electrocardiograms were obtained to assess heart rate, cardiac sympathetic index ( CSI ), and cardiac vagal index ( CVI ) before and after awakening. MHPG levels increased significantly during the first 30 min after awakening. Similarly, cortisol, heart rate, and CSI increased during the 30 min after awakening, but changes in MHPG did not correlate with changes in cortisol, heart rate, CSI , and CVI during that period. This study demonstrated that salivary MHPG levels increase after awakening, in common with cortisol, heart rate, and cardiac sympathetic activity.