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Physical comorbidities in older adults receiving antidepressants in Asia
Author(s) -
Zhong XiaoMei,
Dong Min,
Wang Fei,
Zhang Qinge,
Ungvari Gabor S.,
Ng Chee H.,
Chiu Helen F.K.,
Si TianMei,
Sim Kang,
Avasthi Ajit,
Grover Sandeep,
Chong MianYoon,
Chee KokYoon,
Kanba Shigenobu,
Lee MinSoo,
Yang ShuYu,
Udomratn Pichet,
Kallivayalil Roy A.,
Tanra Andi J.,
Maramis Margarita M.,
Shen Winston W.,
Sartorius Norman,
Mahendran Rathi,
Tan ChayHoon,
Shinfuku Naotaka,
Xiang YuTao
Publication year - 2018
Publication title -
psychogeriatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 32
eISSN - 1479-8301
pISSN - 1346-3500
DOI - 10.1111/psyg.12327
Subject(s) - medicine , psychiatry , comorbidity , cohort , depression (economics) , polypharmacy , anxiety , medical prescription , logistic regression , mood , mood disorders , economics , pharmacology , macroeconomics
Background The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP‐AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.