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Effectiveness of low‐dose pregabalin in three patients with L ewy body disease and central neuropathic pain
Author(s) -
Ukai Katsuyuki,
Fujishiro Hiroshige,
Ozaki Norio
Publication year - 2017
Publication title -
psychogeriatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 32
eISSN - 1479-8301
pISSN - 1346-3500
DOI - 10.1111/psyg.12192
Subject(s) - pregabalin , medicine , neuropathic pain , disease , central pain , lewy body , dementia , dementia with lewy bodies , anesthesia
Many patients with L ewy body disease complain of pain, and their pain may be associated with this disease. Recently, pain has become a focus of attention in P arkinson's disease, but there is little information regarding pain in patients who have dementia with L ewy bodies. We used pregabalin to treat three L ewy body disease patients with chronic pain that may have been related to degeneration of central neurons. All three patients responded well to pregabalin at 25–50 mg/day. To our knowledge, there have been no previous reports of pregabalin showing efficacy for central neuropathic pain in P arkinson's disease or L ewy body disease.