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Evaluation of regional cerebral blood flow in patient with atypical senile dementia with asymmetrical calcification
Author(s) -
Shoyama Masaru,
Ukai Satoshi,
Shinosaki Kazuhiro
Publication year - 2015
Publication title -
psychogeriatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 32
eISSN - 1479-8301
pISSN - 1346-3500
DOI - 10.1111/psyg.12110
Subject(s) - cerebral blood flow , calcification , medicine , dementia , pathology , basal ganglia , single photon emission computed tomography , atrophy , frontotemporal dementia , cardiology , radiology , central nervous system , disease
We report an 83‐year‐old woman with atypical senile dementia with F ahr‐type calcification. Brain computed tomography demonstrated asymmetrical calcification predominant in the basal ganglia on the right side and pronounced diffuse cortical atrophy in the frontotemporal areas. The patient was clinically diagnosed with diffuse neurofibrillary tangles with calcification. Brain single photon emission computed tomography findings revealed that cerebral blood flow was reduced on the right side, as compared with the left side, in widespread areas. Hemispheric asymmetry in both calcification and cerebral blood flow suggests a relationship between calcification and vascular changes.