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Three patients with mood disorders showing catatonia and frontotemporal lobes atrophy
Author(s) -
Utumi Yushi,
Iseki Eizo,
Arai Heii
Publication year - 2013
Publication title -
psychogeriatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 32
eISSN - 1479-8301
pISSN - 1346-3500
DOI - 10.1111/psyg.12027
Subject(s) - catatonia , frontotemporal dementia , lorazepam , electroconvulsive therapy , mood disorders , psychology , frontal lobe , delirium , mood , atrophy , psychiatry , medicine , dementia , schizophrenia (object oriented programming) , anxiety , disease
Here we report the cases of three patients with mood disorders showing catatonia and frontotemporal lobe atrophy. Catatonia is a syndrome linked to frontal dysfunction that most frequently occurs in patients with mood disorders. The diagnostic criteria of catatonia and frontotemporal dementia partly overlap. In the present patients, catatonia might be closely related to frontal dysfunction caused by frontotemporal lobe atrophy. With regard to therapeutics for catatonia, we found that administering a low dose of lorazepam alone or after electroconvulsive therapy may be useful for treating and preventing catatonia. We also found that administering glutaminate antagonists such as memantine may be useful for treating lorazepam‐resistant catatonia.