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Research on growth factors in periodontology
Author(s) -
Smith Patricio C.,
Martínez Constanza,
Cáceres Mónica,
Martínez Jorge
Publication year - 2015
Publication title -
periodontology 2000
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.725
H-Index - 122
eISSN - 1600-0757
pISSN - 0906-6713
DOI - 10.1111/prd.12068
Subject(s) - periodontology , medicine , regeneration (biology) , wound healing , dentistry , periodontal fiber , cell growth , microbiology and biotechnology , immunology , biology , genetics
Growth factors play critical roles in periodontal repair through the regulation of cell behavior. Many of the cell responses regulated by these proteins include cell adhesion, migration, proliferation and differentiation. Periodontal regeneration involves an organized response of different cells, tissues and growth factors implicated in the coordination of these events. However, periodontal tissue reconstruction is an extremely difficult task. Multiple studies have been performed to understand the specific role of growth factors in periodontal wound healing. In the present review we analyze the evidence that supports the roles of growth factors in periodontal wound healing and regeneration.