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Gestational weight gain and delivery outcomes: A population‐based cohort study
Author(s) -
Xu Huiling,
Arkema Elizabeth V.,
Cnattingius Sven,
Stephansson Olof,
Johansson Kari
Publication year - 2021
Publication title -
paediatric and perinatal epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.667
H-Index - 88
eISSN - 1365-3016
pISSN - 0269-5022
DOI - 10.1111/ppe.12709
Subject(s) - medicine , obstetrics , weight gain , underweight , pregnancy , body mass index , overweight , vaginal delivery , population , gestational age , relative risk , cohort study , gestational diabetes , cohort , confidence interval , gestation , body weight , environmental health , biology , genetics
Background Gestational weight gain is a modifiable factor that could impact maternal and infant health. However, its effect on delivery outcomes is not well established. Objectives To investigate the associations between gestational weight gain and delivery outcomes stratified by early‐pregnancy body mass index (BMI). Methods The study population included singleton livebirths in the Stockholm‐Gotland obstetric cohort (January 2008 to October 2014; n = 174 953). The exposure was total gestational weight gain standardised into gestational‐age‐specific z‐scores by using previously defined Swedish pregnancy weight gain‐for‐gestational age charts. The outcomes included caesarean delivery (overall, elective, and emergency), instrumental vaginal delivery, induction of labour, and postpartum haemorrhage. Confounders included maternal age, maternal height, parity, smoking status, cohabitation status, chronic hypertension, and pre‐pregnancy diabetes. Logistic regression models with marginal standardisation were used to estimate risk ratios (RR) with 95% confidence intervals (CI) for each delivery outcome stratified by early‐pregnancy BMI. Results Above average weight gain (z‐score ≥ 0.50 SD) increased risks of caesarean delivery (from RR 1.08, 95% CI 1.00, 1.15 to RR 1.45, 95% CI 1.35, 1.55 across BMI groups), induction of labour (from RR 1.14, 95% CI 1.04, 1.23 to RR 1.38, 95% CI 1.25, 1.51 across BMI groups except underweight), and postpartum haemorrhage (from RR 1.13, 95% CI 1.07, 1.19 to RR 1.25, 95% CI 1.09, 1.41 among normal and overweight). Below average weight gain (z‐score <−0.50 SD) decreased caesarean delivery risk (from RR 0.77, 95% CI 0.61, 0.93 to RR 0.89, 95% CI 0.84, 0.95 across BMI groups except underweight). Conclusions In normal and overweight women, the risks of caesarean delivery, induction of labour, and postpartum haemorrhage increased with gestational weight gain. In obese women, higher gestational weight gain increased risks of caesarean delivery and induction of labour. Low gestational weight gain reduced risk of caesarean delivery in all BMI groups except underweight.