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Effect of hepatitis C infection on the quality of life
Author(s) -
Horváth Gergely,
Keleti Teodóra,
Makara Mihály,
Ungvari Gabor S.,
Gazdag Gábor
Publication year - 2018
Publication title -
perspectives in psychiatric care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.538
H-Index - 35
eISSN - 1744-6163
pISSN - 0031-5990
DOI - 10.1111/ppc.12269
Subject(s) - medicine , quality of life (healthcare) , beck depression inventory , depression (economics) , cohort , hepatitis c , population , cirrhosis , cross sectional study , multivariate analysis , cohort study , clinical psychology , gerontology , psychiatry , pathology , anxiety , nursing , environmental health , economics , macroeconomics
Purpose To assess the quality of life (QoL) of patients with hepatitis C infection (HCI) and its correlations with demographic and clinical variables. Design and Methods QoL and depressive symptoms were evaluated with the validated rating instruments of the 36‐item short form (SF‐36) generic health survey and the second version of the self‐rated Beck depression inventory (BDI‐II) in a cross‐sectional design and correlated with basic demographic and clinical variables, including the Fibroscan score, which indicates the severity of liver impairment. Findings A cohort of 60 HCI patients who participated in the study scored lower than the general population on all domains of the SF‐36. In the multivariate correlation analysis, only the physical functioning domain of the SF‐36 showed a significant correlation with age, gender, and BD‐II and Fibroscan scores. Implications for Clinical Practice QoL is lower for patients who are older, female, and have depressive symptoms. Progression of hepatic cirrhosis is associated with lower QoL in the physical domain.