Ropinirole in Bipolar Disorder: Rate of Manic Switching and Change in Disease Severity | Zendy

Capote Horacio A. | Zendy; Rainka Michelle | Zendy; Westphal Erica S. | Zendy; Beecher Jonathan | Zendy; Gengo Francis M. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Ropinirole in Bipolar Disorder: Rate of Manic Switching and Change in Disease Severity

Author(s) -

Capote Horacio A.,

Rainka Michelle,

Westphal Erica S.,

Beecher Jonathan,

Gengo Francis M.

Publication year - 2018

Publication title -

perspectives in psychiatric care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.538

H-Index - 35

eISSN - 1744-6163

pISSN - 0031-5990

DOI - 10.1111/ppc.12205

Subject(s) - young mania rating scale , ropinirole , mania , bipolar disorder , clinical global impression , psychology , rating scale , psychiatry , bipolar i disorder , medicine , disease , mood , developmental psychology , levodopa , alternative medicine , pathology , parkinson's disease , placebo

PURPOSE To determine the effects of ropinirole on manic switching and disease severity in bipolar disorder. DESIGN AND METHODS A cross‐sectional survey was conducted in 23 bipolar depressed patients using ropinirole combination therapy (Young Mania Rating Scale [YMRS], Bipolar Inventory of Symptoms Scale [BISS]). Retrospective Clinical Global Impression of Change (CGI‐C) and CGI‐S (Severity) were captured via chart review. FINDINGS One patient (4.3%) experienced induction of mania (YMRS). All patients responded or partially responded to ropinirole (CGIs). YMRS and BISS mania scores were correlated. PRACTICE IMPLICATIONS Ropinirole has a low rate of manic switching and significantly reduces bipolar depression severity.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research