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A Case of Congenital Infantile Fibrosarcoma of the Bowel Presenting as a Neonatal Intussusception
Author(s) -
Obayashi Juma,
Koizumi Hirotaka,
Hoshikawa Masahiro,
Wakisaka Munechika,
Fujikawa Atsuko,
Kitagawa Hiroaki,
Takagi Masayuki
Publication year - 2017
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/pin.12603
Subject(s) - intussusception (medical disorder) , medicine , pathological , fibrosarcoma , pathology , radiology
Neonatal intussusception of the intestinal tract is rare. However, most neonatal intussusceptions have an organic lead point. For the lead point to be a neoplasm is extremely rare. We report a case that presented with neonatal intussusception with a congenital infantile fibrosarcoma as the lead point. The detection of ETV6‐NTRK3 gene fusion was useful, although the definitive diagnosis was achieved by a comprehensive evaluation including this gene analysis, standard histology and immunohistochemistry. Neonatal intussusception should be suspected to be caused by a neoplasm. If pathological diagnosis is difficult, molecular analysis should be utilized to diagnose congenital infantile fibrosarcoma.

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