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Case of solitary pulmonary capillary hemangioma: Pathological features based on frozen section analysis
Author(s) -
Isaka Tetsuya,
Yokose Tomoyuki,
Ito Hiroyuki,
Washimi Kota,
Imamura Naoko,
Watanabe Masato,
Imai Kentaro,
Nishii Teppei,
Yamada Kouzo,
Nakayama Haruhiko,
Masuda Munetaka
Publication year - 2013
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/pin.12120
Subject(s) - pathological , pathology , frozen section procedure , capillary hemangioma , section (typography) , hemangioma , medicine , computer science , operating system
Solitary pulmonary capillary hemangioma ( SPCH ) is a rare benign lung tumor that must be distinguished from small and early lung cancers. Here, we report a case of SPCH for which we performed frozen section diagnosis. The patient was a 55‐year‐old J apanese woman. Five years before the operation, mixed ground‐glass opacity was detected by computed tomography in the left posterior basal segment of the lower lobe ( S10 ). Because the interior tumor density of the ground‐glass opacity increased slightly, video‐assisted thoracic surgery wedge resection was performed. Frozen section diagnosis revealed a benign tumor without proliferation of atypical epithelial cells. The tumor had narrow alveolar lumens, thickened alveolar septa and a clear boundary separating it from normal lung tissue. The proliferated lumens varied in size and were lined with single layers of flat cells. After the operation, immunohistochemical staining of a paraffin section revealed that the thickened alveolar septa resulted from the proliferation of capillary vessels, the flat cells of which were positive for CD31 and CD34 and negative for podoplanin; the tumor was diagnosed as SPCH . Here, we discuss the pathological features of SPCH on frozen sections with reference to this case and review previous related reports.