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UVR protection influences fructosamine level after sun exposure of healthy adults
Author(s) -
Mianowska Beata,
Narbutt Joanna,
Young Antony Richard,
Fendler Wojciech,
Małachowska Beata,
Młynarski Wojciech,
Lesiak Aleksandra
Publication year - 2016
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/phpp.12274
Subject(s) - fructosamine , sunbathing , hemoglobin , glycation , glycated hemoglobin , significant difference , zoology , chemistry , medicine , endocrinology , biology , diabetes mellitus , type 2 diabetes , dermatology
Summary Background Seasonal variation in glycated hemoglobin levels has been observed, and sun exposure has been considered as one of the factors associated with this relationship. Fructosamine is a short‐time marker of blood protein glycation. Aim We investigated the effect of seven days of sunbathing on blood fructosamine concentration in healthy volunteers using different ultraviolet radiation ( UVR ) protections. Materials and Methods Participants were assigned to one of three groups: group A – used a UVA and UVB absorbing sunscreen ( N = 15), group B – used a UVB absorbing sunscreen ( N = 18), and group C – followed uncontrolled sun protection habits ( N = 22). Results Overall, the fructosamine concentration did not change after sun exposure (baseline 248.8 μmol/l, 25–75%: 238.5 to 258.8 μmol/l vs. after 247.3 μmol/l, 25–75%: 234.9 to 261.8 μmol/l, P = 0.6637). Median change of fructosamine differed significantly between groups (A: −1.90 μmol/l, 25–75%: −17.10 to 1.80 μmol/l vs. B: −3.80 μmol/l, 25–75%: −18.50 to 2.40 μmol/l vs. C: +4.05 μmol/l, 25–75%: −3.20 to 22.0 μmol/l; one‐way ANOVA P = 0.0277). After age adjustment and combining groups A and B, the difference in change of fructosamine concentration was statistically significant between groups A + B (decrease) vs. group C (increase, P = 0.0193). Conclusion Appropriate sunscreen use during sunbathing resulted in decreased fructosamine concentrations, while inadequate UVR protection resulted in its increase.