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Interoperability of 300 watt and 150 watt xenon arc solar simulators in sun protection factor and in UVA protection factor clinical testing
Author(s) -
Martinez Alexa,
Roberts Glenn,
Garzarella Katherine,
Lutz Michael,
Caswell Michael
Publication year - 2013
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/phpp.12023
Subject(s) - sun protection factor , watt , food and drug administration , analytical chemistry (journal) , physics , medicine , chemistry , chromatography , pharmacology , dermatology , power (physics) , quantum mechanics
Summary Background The purpose of these clinical trials was to determine if 300 W and 150 W xenon arc solar simulators ( SS s) deliver the same sun protection factor ( SPF ) and UVA protection factor ( PFA ). Methods First, the SPF of the P 7 control standard and of the P 2 control standard was determined, testing 20 subjects using the method described in the Food and Drug Administration ( FDA ) F inal M onograph and using 150 W and 300 W SS s. In the second clinical trial, the PFA of the Japanese Cosmetic Industry Association ( JCIA ) control standard and of the P 2 control standard was determined, testing 10 subjects using the method described in the JCIA T echnical B ulleti n and using 150 W and 300 W SS s. Results The SPF values for P 7 control standard determined using the 150 W and 300 W SS s were 4.54 ± 0.35 and 4.61 ± 0.32, respectively. The SPF values for P 2 control standard determined using the 150 W and 300 W SS s were 17.0 ± 0.9 and 16.7 ± 0.9, respectively. The resultant PFA values for JCIA control standard determined using the 150 W and 300 W SS s were 4.06 ± 0.70 and 4.06 ± 0.70, respectively. The resultant PFA values for P 2 control standard determined using the 150 W and 300 W SS s were 3.28 ± 0.25 and 3.44 ± 0.39, respectively. Conclusion As the values are essentially identical for SPF and for PFA , the 150 W and 300 W SS s can be used interchangeably for SPF and PFA determinations.