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Generation of Singlet Molecular Oxygen by Lipid Hydroperoxides and Nitronium Ion †
Author(s) -
Prado Fernanda M.,
Scalfo Alexsandra C.,
Miyamoto Sayuri,
Medeiros Marisa H.G.,
Di Mascio Paolo
Publication year - 2020
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/php.13236
Subject(s) - singlet oxygen , chemistry , photochemistry , oxygen , ion , reactive oxygen species , singlet state , molecular oxygen , excited state , organic chemistry , biochemistry , physics , nuclear physics
Singlet molecular oxygen is a reactive species involved in biological oxidative processes. The major cellular targets of singlet molecular oxygen are unsaturated fatty acids in the membrane, as well as nucleic acids and proteins. The aim of this study was to investigate whether lipids and commercial hydroperoxides generate singlet molecular oxygen, in presence of nitronium and activated nitronium ion. For this purpose, monomol light emitted in the near‐infrared region (λ = 1270 nm) was used to monitor singlet molecular oxygen decay in different solvents, with different hydroperoxides and in the presence of azide. Direct measurements of the singlet molecular oxygen spectrum at 1270 nm recorded during the reaction between lipids and commercial hydroperoxides and nitronium ions unequivocally demonstrated the formation of this excited species.