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Effects of Photobiomodulation on SOFAT , A T‐cell‐derived Cytokine, May Explain Accelerated Orthodontic Tooth Movement
Author(s) -
Jettar Viviane,
Napimoga Marcelo H.,
Freitas Fabiana,
ClementeNapimoga Juliana T.,
Suzuki Selly S.,
Montalli Victor A.,
Garcez Aguinaldo S.
Publication year - 2018
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/php.12878
Subject(s) - osteoclast , bone remodeling , displacement (psychology) , cytokine , dentistry , orthodontics , medicine , chemistry , psychology , receptor , psychotherapist
Orthodontic tooth movement is based on mechanical forces inducing bone remodeling, and several methods have been proposed to increase tooth movement, including photobiomodulation. This study evaluated, in an animal model, the effects of photobiomodulation on SOFAT —a secreted osteoclastogenic factor of activated T cells and RANK ‐L during tooth movement. The results showed that tooth displacement, RANK ‐L and SOFAT levels were significantly greater compared to Control group. SOFAT may play an important role in bone remodeling during orthodontic movement, possibly increasing the osteoclast cells at the compression area and bone remodeling activity.