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Nonvisual Opsins and the Regulation of Peripheral Clocks by Light and Hormones
Author(s) -
Poletini Maristela O.,
Ramos Bruno C.,
Moraes Maria Nathalia,
Castrucci Ana Maria L.
Publication year - 2015
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/php.12494
Subject(s) - opsin , hormone , peripheral , neuroscience , biology , microbiology and biotechnology , medicine , endocrinology , biochemistry , rhodopsin , retinal
The molecular clock machinery is conserved throughout evolution. However, how environmental cues are perceived has evolved in such a way that peripheral clocks in mammals require a variety of signals, including hormones. On the other hand, in nonmammalian cells able to directly detect light, light seems to play a major role in the synchronization of the clock. The interaction between perception of circadian light by nonvisual opsins and hormones will be discussed under the perspective of clock synchronization at the molecular level.