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Photoresponsive Cross‐linked Polymeric Particles for Phototriggered Burst Release
Author(s) -
Wang Zhen,
Yu Lili,
Lv Cong,
Wang Peng,
Chen Yedong,
Tang Xinjing
Publication year - 2013
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/php.12038
Subject(s) - miniemulsion , nile red , monomer , fluorescence , photochemistry , polymerization , particle (ecology) , chemistry , chemical engineering , breakage , polymer chemistry , polymer , materials science , organic chemistry , optics , physics , oceanography , engineering , composite material , geology
We synthesized a series of cross‐linked photoresponsive polymeric particles with photolabile monomers and cross‐linkers through miniemulsion polymerization. These particles are quite stable in dark, while light irradiation caused the breakage of particles and the efficient release of encapsulated contents up to 95% based on Nile red fluorescence. Photoswitches of particle systems were confirmed by fluorescence spectroscopy, SEM and colorimetry. Particle uptake and triggered release in RAW 264.7 cells were confirmed by fluorescein diacetate loaded particles.