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Outcomes of pediatric liver transplant are unaffected by the time or day of surgery
Author(s) -
Rogers Michael E.,
Egberg Matthew D.,
Sylvester Francisco,
Lichtman Steven,
Lin FengChang
Publication year - 2020
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13826
Subject(s) - medicine , confounding , hazard ratio , proportional hazards model , surgery , liver transplantation , weekend effect , transplantation , emergency medicine , confidence interval
Background In adults, the time of day for LT does not affect post‐transplant outcomes. Whether this is true or not in children is unknown. In this study, we aimed to evaluate if weekend and weeknight liver transplants are associated with worse patient and graft survival in children. Methods We interrogated the UNOS database for outcomes of pediatric liver transplants that occurred between 1988 and 2018. We excluded liver transplants in patients >17 years as well as all multiple organ transplants. We compared weeknight and weekday, as well as weekend transplant operations. We used Cox proportional hazard ratios to determine patient and graft survival by 7, 30, 90, and 365 days post‐transplant after controlling for confounding factors. Results In total, 12,610 pediatric liver transplants were included in the analysis. A total of 4590 transplants occurred during weekdays, 3671 transplants occurred during weeknights, and 4349 occurred during weekends. After controlling for confounding variables, 1‐year patient survival was not associated with worse outcomes if the transplant occurred on the weeknight (HR 0.94, 95%CI 0.74‐1.21) or weekend (HR 0.95, 95%CI 0.75‐1.20) compared to the weekday. One‐year graft survival was also not associated with worse outcomes if the transplant occurred on the weeknight (HR 0.91, 95%CI 0.76‐1.09) or weekend (HR 0.91, 95%CI 0.77‐1.09) compared to the weekday. Conclusion Weekday, weeknight, and weekend procedures resulted in similar 1‐year survival rates. Pediatric patient and graft survival outcomes are not affected by the time or day of surgery.