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Bartonella henselae infection in the pediatric solid organ transplant recipient
Author(s) -
Lopez Santiago Manuel Cayetano,
Davis Amy,
Zinn Matthew,
Feingold Brian,
Green Michael,
Michaels Marian G.
Publication year - 2021
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13823
Subject(s) - bartonella henselae , medicine , bartonella , organ transplantation , solid organ , serology , population , bacillary angiomatosis , immunology , pathology , transplantation , virology , environmental health , antibody
Bartonella henselae infection can cause a wide spectrum of diseases in both the immunocompetent and immunocompromised host with BA a severe form relegated to immunocompromised hosts, including solid organ transplant population. There are established criteria for diagnosis of Bartonella infection based on clinical presentation, serologic testing, imaging studies and, when indicated, tissue sampling for histopathological evaluation, particularly for BA. However, treatment recommendations for BA are inconclusive. Furthermore, there are no studies in the pediatric solid organ transplant population for antimicrobial therapy during BA secondary to Bartonella henselae infection. A case of BA following heart transplant is presented along with a literature review of clinical presentation; diagnosis and therapy for BA in the pediatric solid organ transplant population.