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Varying presentations of COVID‐19 in young heart transplant recipients: A case series
Author(s) -
Lee Hannah,
Mantell Benjamin S.,
Richmond Marc E.,
Law Sabrina P.,
Zuckerman Warren A.,
Addonizio Linda J.,
Lee Teresa M.,
Lytrivi Irene D.
Publication year - 2020
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13780
Subject(s) - medicine , immunosuppression , covid-19 , disease , pandemic , heart transplantation , presentation (obstetrics) , pediatrics , intensive care medicine , transplantation , young adult , surgery , infectious disease (medical specialty)
Background Immunosuppression is considered a risk factor for more severe clinical presentation of COVID‐19. Limited data regarding clinical outcome exist in adults, whereas very little is known about the spectrum of the disease in pediatric heart transplant recipients. Methods We retrospectively reviewed the charts of young heart transplant patients from our tertiary care center during the coronavirus pandemic in New York City and identified patients infected with SARS‐CoV‐2. Results We present four cases with COVID‐19 disease and elaborate on their presentation and clinical course. Conclusions Although far from conclusive and limited by the small sample size and selection bias, these cases demonstrate mild and self‐limited disease despite immunosuppressive therapy and various comorbidities that are expected to increase the severity of the clinical picture based on extrapolation from the adult experience with this novel disease.

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