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Emerging arboviruses and implications for pediatric transplantation: A review
Author(s) -
Freeman Megan Culler,
Coyne Carolyn B.,
Green Michael,
Williams John V.,
Silva Laurie A.
Publication year - 2019
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13303
Subject(s) - medicine , population , transplantation , incidence (geometry) , immunology , virology , colonization , intensive care medicine , environmental health , biology , ecology , physics , surgery , optics
Recent years have brought a rise in newly emergent viral infections, primarily in the form of previously known arthropod‐transmitted viruses that have increased significantly in both incidence and geographical range. Of particular note are DENV, CHIKV, and ZIKV, which are transmitted mostly by Aedes species of mosquitoes that exhibit a wide and increasing global distribution. Being important pathogens for the general population, these viruses have the potential to be devastating in the international transplant community, with graft rejection and death as possible outcomes of infection. In this review, we discuss the current state of knowledge for these viruses as well as repercussions of infection in the solid organ and HSCT population, with a focus, when possible, on pediatric patients.