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A case series of perioperative variables in relation to short‐term outcomes in pediatric renal transplant recipients
Author(s) -
Goh Celine Y. Y.,
HumeSmith Helen,
Kessaris Nicos,
Marks Stephen D.
Publication year - 2018
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13198
Subject(s) - medicine , anastomosis , perioperative , surgery , perfusion , retrospective cohort study
Multiple perioperative variables have been shown in existing literature to influence long‐term outcomes of pediatric RTx, such as allograft survival. Their impact on short‐term outcomes is not as well‐documented. This case series aims to investigate the effects of nine perioperative variables on two short‐term outcomes in pRTR : 1‐week post‐operative eGFR and post‐operative LOS . A total of 73 pRTR transplanted over 3 years from 2012 to 2014 at a single center were studied retrospectively and statistical analyses were performed. There was higher 1‐week post‐operative eGFR in pRTR who received living donor transplants compared to those who received deceased donor transplants ( P =.01), with mean eGFR of 135 mL/min/1.73 m 2 and 82 mL/min/1.73 m 2 , respectively. Aorta‐ IVC anastomosis was associated with longer LOS compared to iliac vessel anastomosis ( P =.03), with median LOS of 19 and 13 days, respectively. There were no significant effects on 1‐week eGFR or LOS of the seven other variables: pRTR age and gender, donor age, preoperative donor SBP , intraoperative mean CVP before graft perfusion, intraoperative median SBP z score after graft perfusion, and intraoperative fluid volume. Living donor transplants were associated with higher 1‐week post‐operative eGFR compared to deceased donor transplants. Aorta‐ IVC anastomosis was significantly associated with longer LOS compared to iliac vessel anastomosis.