Premium
Disseminated fungal infection by Aureobasidium pullulans in a renal transplant recipient
Author(s) -
Nalcacioglu Hulya,
Yakupoglu Y. Kamil,
Genc Gurkan,
Belet Nursen,
Sensoy Sema Gulnar,
Birinci Asuman,
Ozkaya Ozan
Publication year - 2018
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13152
Subject(s) - aureobasidium pullulans , voriconazole , medicine , opportunistic infection , renal transplant , mycosis , amphotericin b , phaeohyphomycosis , itraconazole , microbiology and biotechnology , transplantation , immunosuppression , aspergillosis , dermatology , immunology , antifungal , biology , surgery , human immunodeficiency virus (hiv) , viral disease , food science , fermentation
Abstract Renal transplant recipients are on long‐term potent immunosuppressive therapy, which makes them highly vulnerable to opportunistic fungal infections. Dematiaceous, or dark‐pigmented saprophytic fungi, are being increasingly seen as opportunistic pathogens of mycoses in immunosuppressed patients. One of these is Aureobasidium pullulans , which is a black yeast‐like dematiaceous fungus found ubiquitously in the environment that can cause various opportunistic human infections. Most infections occur by traumatic inoculation, such as keratitis and cutaneous lesions; disseminated mycoses are very rare and occur only in severely immunocompromised patients. We report a case of disseminated fungal infection due to A. pullulans in a pediatric patient who underwent renal transplant. The use of voriconazole and vacuum‐assisted closure along with surgical drainage most likely contributed to the patient's positive outcome.