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World's smallest combined en bloc liver‐pancreas transplantation
Author(s) -
Elsabbagh Ahmed M.,
Hawksworth Jason,
Khan Khalid M.,
Yazigi Nada,
Matsumoto Cal S.,
Fishbein Thomas M.
Publication year - 2018
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13082
Subject(s) - medicine , neutropenia , pancreas , concomitant , diabetes mellitus , liver transplantation , fulminant , pediatrics , surgery , gastroenterology , transplantation , endocrinology , chemotherapy
We present a case of a 2‐year‐old child who underwent a combined en bloc liver and pancreas transplant following complications of WRS. WRS is characterized clinically through infantile insulin‐dependent diabetes mellitus, neutropenia, recurrent infections, propensity for liver failure following viral infections, bone dysplasia, and developmental delay. Usually, death occurs from fulminant liver and concomitant kidney failure. Few cases with WRS are reported in the literature, mostly from consanguineous parents. To the best of our knowledge, combined en bloc liver and pancreas transplant has not been performed in small children.