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Successful liver transplantation for non‐resectable desmoplastic nested spindle cell tumor complicated by Cushing's syndrome
Author(s) -
Tehseen Sarah,
Rapkin Louis,
Schemankewitz Erwin,
Magliocca Joseph F.,
Romero Rene
Publication year - 2017
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.13000
Subject(s) - medicine , metastasis , stroma , liver transplantation , pathology , transplantation , primary tumor , immunohistochemistry , surgery , cancer
Desmoplastic spindle cell tumors of liver are rare tumors of low malignant potential characterized by well‐demarcated nests of spindle and epithelioid cells in a dense desmoplastic stroma. While surgery remains the definitive treatment, there have been reports of tumor recurrence locally and metastasis which respond poorly to chemotherapy. Hepatic transplant has been attempted in cases of recurrence or large size of primary tumor. Long‐term follow‐up and imaging surveillance are required as these tumors have shown a tendency for recurrence many years after initial therapy.