Successful treatment with placenta‐derived decidual stromal cells in a pediatric patient with life‐threatening acute gastrointestinal graft‐versus‐host disease | Zendy

Gustafsson Britt | Zendy; Frisk Per | Zendy; Szakos Attilla | Zendy; Sadeghi Behnam | Zendy; Ringdén Olle | Zendy; Frost BrittMarie | Zendy

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Successful treatment with placenta‐derived decidual stromal cells in a pediatric patient with life‐threatening acute gastrointestinal graft‐versus‐host disease

Author(s) -

Gustafsson Britt,

Frisk Per,

Szakos Attilla,

Sadeghi Behnam,

Ringdén Olle,

Frost BrittMarie

Publication year - 2017

Publication title -

pediatric transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 69

eISSN - 1399-3046

pISSN - 1397-3142

DOI - 10.1111/petr.12990

Subject(s) - medicine , stromal cell , disease , complication , placenta , graft versus host disease , pregnancy , gastrointestinal tract , immunology , gastroenterology , fetus , biology , genetics

Severe aGv HD is a life‐threatening complication after allogeneic HSCT . The GI tract is considered to play a key role in aGvHD , where the disease process can start and is one of the major target organs. Here, we present a case of a one‐year‐old child with a life‐threatening GI ‐ aGvHD stage IV , post‐ HSCT , resistant to steroids and MMF for 4 weeks. He was successfully treated with placenta‐derived DSC.

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