Premium
Successful treatment with placenta‐derived decidual stromal cells in a pediatric patient with life‐threatening acute gastrointestinal graft‐versus‐host disease
Author(s) -
Gustafsson Britt,
Frisk Per,
Szakos Attilla,
Sadeghi Behnam,
Ringdén Olle,
Frost BrittMarie
Publication year - 2017
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12990
Subject(s) - medicine , stromal cell , disease , complication , placenta , graft versus host disease , pregnancy , gastrointestinal tract , immunology , gastroenterology , fetus , biology , genetics
Severe aGv HD is a life‐threatening complication after allogeneic HSCT . The GI tract is considered to play a key role in aGvHD , where the disease process can start and is one of the major target organs. Here, we present a case of a one‐year‐old child with a life‐threatening GI ‐ aGvHD stage IV , post‐ HSCT , resistant to steroids and MMF for 4 weeks. He was successfully treated with placenta‐derived DSC.