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Survival outcomes scores ( SOFT , BAR , and Pedi‐ SOFT ) are accurate in predicting post‐liver transplant survival in adolescents
Author(s) -
Conjeevaram Selvakumar Praveen Kumar,
Maksimak Brian,
Hanouneh Ibrahim,
Youssef Dalia H.,
Lopez Rocio,
Alkhouri Naim
Publication year - 2016
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12770
Subject(s) - medicine , soft tissue , survival rate , survival analysis , retrospective cohort study , overall survival , surgery
SOFT and BAR scores utilize recipient, donor, and graft factors to predict the 3‐month survival after LT in adults (≥18 years). Recently, Pedi‐ SOFT score was developed to predict 3‐month survival after LT in young children (≤12 years). These scoring systems have not been studied in adolescent patients (13–17 years). We evaluated the accuracy of these scoring systems in predicting the 3‐month post‐ LT survival in adolescents through a retrospective analysis of data from UNOS of patients aged 13–17 years who received LT between 03/01/2002 and 12/31/2012. Recipients of combined organ transplants, donation after cardiac death, or living donor graft were excluded. A total of 711 adolescent LT recipients were included with a mean age of 15.2±1.4 years. A total of 100 patients died post‐ LT including 33 within 3 months. SOFT , BAR , and Pedi‐ SOFT scores were all found to be good predictors of 3‐month post‐transplant survival outcome with areas under the ROC curve of 0.81, 0.80, and 0.81, respectively. All three scores provided good accuracy for predicting 3‐month survival post‐ LT in adolescents and may help clinical decision making to optimize survival rate and organ utilization.