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Severe West Nile virus meningoencephalitis in a pediatric renal transplant recipient: successful recovery and long‐term neuropsychological outcome
Author(s) -
Lambert S. L.,
Aviles D.,
Vehaskari V. M.,
Ashoor I. F.
Publication year - 2016
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1111/petr.12768
Subject(s) - medicine , meningoencephalitis , immunosuppression , arbovirus , pediatrics , west nile virus , disease , neuropsychology , renal transplant , transplantation , intensive care medicine , immunology , virus , psychiatry , cognition
West Nile Virus is an arbovirus that has rapidly spread throughout the United States since the first case was described in Queens, New York in 1999. There has been increasing reports of both community‐acquired and organ‐derived infections in renal transplant recipients. In immunocompromised individuals, WNV infection is a life‐threatening disease with significant neurological morbidity. We report the only pediatric case of community‐acquired WNV disease in a renal transplant recipient to undergo detailed long‐term neuropsychological assessment. Increased surveillance and prompt treatment of WNV meningoencephalitis is critical, and our report highlights the effectiveness of immunosuppression reduction without compromising allograft outcomes.